Your vet will know what and when vaccines are due in your area.
In my area there are 4 series of shots before the rabies shot. Then they are free to leave the home/yard and go out and socialize with other dogs and new people :)
Canine Distemper
Vaccination against this often fatal, hard-to-treat disease is absolutely essential. Highly contagious, it is spread by discharges from the noses and eyes of infected dogs. Symptoms can include listlessness, fever, coughing, diarrhea and vomiting; convulsions and paralysis may occur in the disease's final stages. The distemper virus attacks many organs, including the nervous system, which may be permanently damaged, even if the dog recovers.
Canine Tracheobronchitis (CANINE COUGH)
Just as with the human common cold, this respiratory-tract infection is easily transmitted from one dog to another, so vaccination is imperative if your pet will come in contact with many other dogs in such situations as obedience training or boarding at a kennel. Caused by various airborne bacteria and viruses, including Canine Parainfluenza virus, Canine Adenovirus Type II and Bordetella Bronchiseptica, you'll first notice its onset by your dog's dry, hacking cough.
Canine Parvovirus
Very contagious, debilitating and widespread, the disease caused by this virus emerged in many parts of the world only in 1978. Spread through infected feces, the highly resistant virus can remain in the environment for many months. Symptoms include high fever, listlessness, vomiting and diarrhea. Vaccination is the only certain method of preventing this potentially fatal disease, which is most severe in young pups and elderly dogs.
Rabies
This incurable viral disease affects the central nervous system of almost all mammals, including humans. It is spread through contact with the saliva of infected animals (which can include skunks, foxes, raccoons and bats) through bites or any break in the skin. Vaccination will provide your pet with much greater resistance to rabies if he is exposed to the disease, but you must be aware that there is no cure once it occurs. For this reason, many municipalities absolutely require that all dogs receive rabies vaccinations on a regular basis. Plus, you will definitely have to prove that your dog is vaccinated if you travel with him - whether across the United States or around the world.
Infectious Canine Hepatitis
Caused by Canine Adenovirus Type I, this disease is transmitted among dogs by contact with secretions, such as saliva, infected urine or feces. Its symptoms are similar to those of the early stages of distemper. Causing liver failure, eye damage and breathing problems, the course of this disease can range from mild to fatal. Vaccination remains the best protection.
Other Vaccinations
After evaluating your dog's particular situation and risk factors, your veterinarian may also recommend vaccination against other infectious diseases. These might include
 LEPTOSPIROSIS, a bacterial disease which attacks the kidneys and liver
CANINE CORONAVIRUS which attacks the intestinal system
LYME DISEASE, transmitted by ticks to both dogs and humans results in chronic arthritis and, sometimes, death. This disease is more common in the northern parts of the United States
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